(* as PI or corresponding author; h-index: 22WoSPubMed, ORCiDPublon updated Dec, 2017)

  1. Mono-allyloxylated Cucurbit[7]uril Acts as an Unconventional Amphiphile to Form Light-responsive Vesicles, Park, K. M.; Baek, K.; Ko, Y. H.; Shrinidhi, A.; Murray J.; Jang, W. H.; Kim, K. H.; Lee, J. S.; Yoo, J.; Kim, S.; Kim. K. Angew. Chem. Int. Ed. Engl., 2018, in press. [link]

  2. Identification of Tumor Initiating Cells by a Small Molecule Fluorescent Probe through Vimentin as the Biomarker, Lee, Y. A.; Kim, J. J.; Lee, J.; Sahu, S.; Kwon, H. Y.; Park, S. J.; Lee, J. H.; Jang, S. Y.; Lee, J. S.; Wang, Z.; Tam, W. L.; Lim, B.; Kang, N. Y.; Chang, Y. T. Angew. Chem. Int. Ed. Engl., 2018, in press. [link]

  3. A vinyl sulfone-based fluorogenic probe capable of selective labeling of PHGDH in live mammalian cells, Pan, S.; Jang, S. Y.; Liew, S. S.; Fu, J.; Wang, D.; Lee, J. S.*; Yao, S. Q.*, Angew. Chem. Int. Ed. Engl., 2018, 57, 579-583. [link]

  4. A novel computational method for biomedical binary data analysis: development of a thyroid disease index using a brute-force search with MLR analysis, Lee, J. K.; Han, W. S.; Lee, J. S.; Yoon, C. N., Bull. Korean Chem. Soc., 2017, 38(12), 1392-1397. [link]

  5. A chemoselective cleavable fluorescence turn-on linker for proteomic studies, Liew, S. S.; Du, S.; Ge, J.; Pan, S.; Jang, S.; Lee, J. S.*; Yao, S. Q.* Chem. Comm. 2017, 53, 13332-13335. [link]

  6. Tetrazole-based probes enable integration of phenotypic screening with target identification and distinct profiling of a cancer biomarker, Chen, K.; Lee, J. S.; Hao, P.; Yao, S. Q.; Ding, K.; Li, Z. Angew. Chem. Int. Ed. Engl., 2017, 56,15044-15048. [link]

  7. Bulk aggregation based fluorescence turn-on sensors for selective detection of progesterone in aqueous solution, Hong, S. C.; Murale, D. P.; Lee, M.; Lee, S. M.; Park, J. S.; Lee, J. S.* Angew. Chem. Int. Ed. Engl., 201756, 14642 –14647. [link]
    - Selected as Hot Paper
    Author interview from BRIC.

  8. A suite of "minimalist" photo-crosslinkers for live-cell imaging and chemical proteomics: Case study with BRD4 inhibitors, Pan, S.; Jang, S. Y.; Wang, D.; Liew S. S.; Li, Z.; Lee, J. S.*; Yao, S. Q.* Angew. Chem. Int. Ed. Engl., 2017, 56, 11816-11821. [link]

  9. Nano metamaterials for ultrasensitive Terahertz biosensing, Lee, D. K.; Kang, J. H.; Kwon J.; Lee, J. S.; Lee, S.; Woo, D. H.; Kim, J. H.; Song, C. S.; Seo, M. Sci. Rep. 2017, 7, 8146. [link]

  10. Cell type selective imaging and profiling of newly synthesized proteomes by using puromycin analogues, Du, S.; Wang, D.; Lee, J. S.; Peng, B.; Ge, J.; Yao, S. Q. Chem. Comm. 2017, 53, 8443-8446. [link]
  11. Photo-affinity labelling (PAL) in chemical proteomics: A handy tool to investigate protein-protein interactions (PPIs), Murale, D. P.; Hong, S. C.; Haque, M. M.; Lee, J. S.* Proteome Sci. 2017, 15:14. [link]

  12. Global mapping of protein-lipid Interactions by using modified choline-containing phospholipids metabolically synthesized in live cells, Wang, D.; Du, S.; Cazenave-Gassiot, A.; Ge, J.; Lee, J. S.; Wenk, M. R.; Yao, S. Q. Angew. Chem. Int. Ed. Engl., 2017, 56, 5829-5833. [link]

  13. β1,6-GlcNAc Linkage to the Core Glycan on TIMP-1 Affects Its Gelatinase Inhibitory Activities: Aberrantly Glycosylated TIMP-1-MMP2 Complex Modeling Shows Weaker Interaction Compared to Bi-antennary Glycosylated TIMP-1, Lee, J. K.; Han, W. S.; Lee, J. S.; Kim, Y. S.; Ko, J. H.; Yoo, J. S.; Yoon, C. N. Bull. Korean Chem. Soc.2017, 38(3), 384-388. [link]

  14. Development of a BODIPY-based fluorescent probe for imaging pathological tau aggregates in live cells, Lim, S.; Haque, M. M.; Su, D.; Kim, D.; Lee, J. S.; Chang, Y. T.; Kim, Y. K. Chem. Comm. 2017, 53, 1607-1610. [link]

  15. In situ proteome profiling and bioimaging applications of small molecule affinity-based probes derived from DOT1L inhibitors, Zhu, B.; Zhang, H.; Pan, S.; Wang, C.; Ge, J.; Lee, J. S.; Yao, S. Q. Chem, Eur. J. 2016, 22, 7824-7836. [link]

  16. Tetrazole photoclick chemistry: Reinvestigating its suitability as a bioorthogonal reaction and potential applications, Li, Z.; Qian, L.; Li, L.; Bernhammer, J. C.; Huynh, H. V.; Lee, J. S.; Yao, S. Q. Angew. Chem. Int. Ed. Engl., 2016, 55, 2002-2006. [link]

  17. Combinatorial dansyl library and its applications to pH-responsive probes, Hong, S. C.; Murale, D. P.; Lee, J. S.* Combi. Chem. High T. Scr. 2016, 19(5), 347-352. [link]

  18. 저분자 프로브를 이용한 분자영상법, Chemworld (화학세계), 2016, 56, 1, p11 [link]

  19. Highly sensitive and selective sugar detection by terahertz nano-antennas, Lee, D. K.; Kang, J. H.; Lee, J. S.; Kim, H. S.; Kim, C.; Kim, J. H.; Lee, T.; Son, J. H.; Park, Q. H.; Seo, M. Sci. Rep. 2015, 5, 15459. [arXiv:1506.08363] [link]

  20. Identification of disulfide cross-linked tau dimer responsible for tau propagation, Kim, D. H.; Lim, S.; Haque, M.; Ryoo, N.; Hong, H. S.; Rhim, H.; Lee, D. E.; Chang, Y. T.; Lee, J. S.; Cheong, E.; Kim, D. J.; Kim, Y. K. Sci. Rep. 2015, 5, 15231. [link]

  21. A small molecule probe capable of selective profiling and imaging of Monoamine Oxidase B activities in Parkinson's Disease models, Li, l.; Zhang, C. W.; Ge, J.; Qian L.; Chai, B. H.; Zhu, Q. Z.; Lee, J. S.;Lim, K. L.; Yao, S. Q. Angew. Chem. Int. Ed. Engl, 2015, 54, 10821-10825. [link]

  22. Rational design of a photo-crosslinking BODIPY for in situ protein labeling, Murale, D. P.; Hong, S. C.; Yun, J.; Yoon, C. N.; Lee, J. S.* Chem. Comm., 2015, 51, 6643-6646[link] 

  23. Chemical proteomic identification of T-plastin as novel host cell response factor in HCV infection, Yoo, Y. H.; Yun, J.; Yoon, C. N.; Lee, J. S.* Sci. Rep., 2015, 5, 9773. [link[Go to GEO dataset]

  24. Unbiased proteomic profiling strategy for discovery of bacterial effector proteins reveals that Salmonella protein PheA is a host cell cycle regulator, Na, H.; Yoo, Y. H.; Yoon, C. N.; Lee, J. S.* Chem. Biol., 2015, 22, 453-459. [link] 
    - Highlighted at "Chemical proteomics of host-pathogen interaction", Chem. Biol., 22, 434. [link]

  25. A small molecule protein-protein interaction inhibitor of PARP1 that targets its BRCT domain, Na, Z.; Peng, B.; Ng, S.; Pan, S.; Lee, J. S.; Shen, H. M.; Yao, S. Q. Angew. Chem. Int. Ed. Engl, 2015, 54, 2515-2519. [link

  26. Diversity oriented approach for chemical biology, Lee, J. S.; Lee, J.W.; Kang, N.; Ha, H.H.; Chang, Y. T. Chem. Rec., 2015, 15, 495-510. [link]
  27. Mechanistic elements and critical factors of cellular reprogramming revealed by stepwise global gene expression analyses, Park, S.J.; Yeo, H.; Kang, N.Y.; Kim, H.; Lin, J.; Ha, H.H.; Vendrell, M.; Lee, J. S.; Chandran, Y.; Lee, D.Y.; Yun, S.W.; Chang, Y. T. Stem Cell Res., 2014, 12(3), 730-741. [link

  28. Proteome reactivity profiling for the discrimination of pathogenic bacteria, Lee, J. S.*; Yoo, Y.H.; Kang, J.H.; Han, W.S.; Lee, J.K.; Yoon, C.N. Chem. Comm., 2014, 50(33), 4347-4350. [link]

  29. Diversity oriented fluorescence library approach (DOFLA) for live cell imaging probe development, Yun, S.W.; Kang, N.Y.; Park, S.J.; Ha, H.H.; Kim, Y.K.; Lee, J. S.; Chang, Y.T. Acc. Chem. Res.2014, 47, 1227-1286. [link]

  30. Small-molecule probes elucidate global enzyme activity in a proteomic context, Lee, J. S.*; Yoo, Y.H.; Yoon, C.N. BMB Rep.2014, 47(3), 149-157. [link]

  31. Focused fluorescent probe library for metal cations and biological anions, Rhee, H.W.; Lee, S.W.; Lee, J. S.; Chang, Y. T.; Hong, J.I. ACS Combi. Sci.2013, 15, 483-490. [link] 

  32. Study of thiazoline derivatives for the design of optimal fungicidal compounds using multiple linear regression (MLR), Han, W. S.; Lee, J. K.; Lee, J. S.; Hahn H.; Yoon, C. N. Bull. Korean Chem. Soc.2012, 33(5), 1703-1706. [link]

  33. Identification of cancer cell-line origins using fluorescence image-based phenomic screening, Lee, J. S.; Kim, Y. K.; Kim, H.; Hajar S.; Tan, Y. L.; Kang, N. Y.; Ng, S. H.; Yoon, C. N.; Chang, Y. T. PLOS ONE2012, 7 (2):e32096e [link] 

    ----- Before PI at KIST -----

  34. Diversity-oriented optical imaging probe development, Lee, J. S.; Vendrell, M.; Chang, Y. T. Curr. Opin. Chem. Biol.2011, 15, 760-767. [link] 

  35. Solid-phase synthesis of BODIPY dyes and development of an immunoglobulin fluorescent sensor, Vendrell, M.; Krishna, G.G.; Ghosh K. K.; Zhai, D.; Lee, J. S.; Zhu, Q.;Yau, Y.H.; Shochat S.G.; Kim, H.; Chung, J.; Chang, Y.T. Chem. Comm.2011, 47, 8424-8426. [link] 

  36. Site-selective labeling at Cys302 of aldehyde dehydrogenase unveils a selective mitochondrial stain, Kim, Y.K.; Lee, J. K.; Lee, J. S.; Yoon, C.N.; Chang, Y.T. Mol. Biosys.,2011, 7, 2375-2378. [link] 

  37. A colorimetric pH indicator and boronic acid ensemble array for quantitative sugar analysis, Ghosh, K.K.; Yap, E.; Kim, H.; Lee, J. S.; Chang, Y.T. Chem. Comm.2011, 47, 4001-4003. [link] 

  38. The binding of fluorophores to proteins depends on the cellular environment, Kim, Y.K.; Lee, J. S.; Bi, X.; Ha, H.H.; Ng, S. H.; Ahn, Y.H.; Lee, J.J.; Wagner, B.K.; Clemons, P.A.; Chang, Y.T. Angew. Chem., Int. Ed. Engl.2011, 50, 2761-2763. [link] 

  39. Accelerating fluorescent sensor discovery: unbiased screening of a diversity-oriented BODIPY library, Lee, J. S.; Kim, H. K.; Feng, S.; Vendrell, M; Chang, Y.T. Chem. Chomm.2011, 47, 2339-2341 [link] 

  40. Fluorescence response profiling for small molecule sensors utilizing the green fluorescent protein chromophore and its derivatives, Lee, J. S.; Baldridge, A.; Feng, S.; Yang, S.; Kim, Y.K.; Tolbert, L.; Chang, Y.T. ACS Combi. Sci.2011, 13, 32-38 [link] 

  41. Synthesis and evaluation of stilbene derivatives as a potential imaging agent of amyloid plaques. Hong, M. C.; Kim, Y. K.; Choi, J.Y.; Yang, S.Q.; Rhee, H.; Ryu, Y.H.; Choi, T.H.; Cheon, G. J.; An, G. I.; Kim, H.Y.; Kim, Y.; Kim, D.J.; Lee, J. S.; Chang, Y.T.; Lee, K.C. Bioorg. Med. Chem. 2010, 18, 7724-7730. [link] 

  42. Quantitative structure-fluorescence property relationship analysis of a large BODIPY library, Schuller A.; Goh G.B.; Lee, J. S.; Chang, Y.T., Mol. Inf., 2010, 29, 717-729. [link] 

  43. A fluorescent rosamine compound selectively stains pluripotent stem cells, Im, C.N.; Kang, N.Y.; Ha, H. H.; Bi, X.; Lee, J.J.; Park, S.J.; Lee, S.Y.; Vendrell, M.; Kim, Y.K.; Lee, J. S.; Li, J.; Ahn, Y.H.; Feng, B.; Ng, H.H.; Yun, S. W.; Chang, Y.T. Angew. Chem., Int. Ed. Engl.2010, 49, 7497-7500. [link] 
    - Highlighted at "Fluorescence method detects stem cells", C&En News, 2010 (September 20), 88 (38), p 25 

  44. Diversity-oriented fluorescence library approaches for probe discovery and development. Vendrell, M.; Lee, J. S.; Chang, Y. T., Curr. Opin. Chem. Biol.2010, 14 (3), 383-389. [link] [Video Abstract]

  45. Isozyme-specific fluorescent inhibitor of glutathione S-transferase omega 1, Son, J; Lee, J. J.; Lee, J. S.; Schuller, A.; Chang, Y. T. ACS Chem. Biol. 2010, 5 (5), 449-453. [link] 

  46. Control of muscle differentiation by a mitochondria-targeted fluorophore, Kim, Y. K.; Ha, H. H.; Lee, J. S.; Bi, X. Z.; Ahn, Y. H.; Hajar, S.; Lee, J. J.; Chang, Y. T. J. Am. Chem. Soc.2010, 132, 576 - 579. [link] 

  47. Colorimetric sensor array for qualitative water analysis, Chan, S. A.; Lee, J. S.; Chang, Y. T. Aust. J. Chem. 2009, 62, 1040-1046. [link] 

  48. Synthesis of a bodipy library and its application to the development of live cell glucagon imaging probe, Lee, J. S.; Kang, N.Y.; Kim, Y. K.; Samanta, A.; Feng, S.; Kim, H.K.; Vendrell, M.; Park, J.H.; Chang, Y. T. J. Am. Chem. Soc. 2009, 131, 10077-10082. [link] 
    Highlighted at JACS Select issue 10: Supramolecular and Chemical Cascade Approaches to Molecular Sensing. 
    Recommended in F1000.

  49. Diversity-oriented fluorescence library approach for the discovery of sensors and probes. Lee, J. S.; Kim,Y.K.; Vendrell, M.; Chang, Y.T. Mol. BioSyst.2009, 5, 411-421. [link] 

  50. A selective human serum albumin sensor from screening of fluorescent rosamine library, Ahn, Y.H.; Lee, J. S.; Chang, Y.T. J. Comb. Chem. 2008, 10, 376-380. [link] 

  51. Counterion free colorimetric metal cation sensor array, Lee, J.S.; Lee, J.W.; Chang, Y.T. J. Comb. Chem. 2007, 9, 926-928.[link] 

  52. Understanding the activity of small molecules in the genomics context (highlight article), Lee, J. S.; Chang, Y.T. Angew. Chem., Int. Ed. Engl.2007, 46, 3616-3618. [link] 

  53. Combinatorial rosamine library and application to in vivo glutathione probe, Ahn, Y.H.; Lee, J. S.; Chang, Y.T. J. Am. Chem. Soc. 2007, 129, 4510-4511. [link] 

  54. Colorimetric identification of carbohydrates by a pH indicator/ pH change inducer ensemble, Lee, J. W.; Lee, J. S.; Chang, Y. T. Angew. Chem., Int. Ed. Engl.2006,45, 6485-6487. [link] 
    - Highlighted at "Discriminating between carbohydrates", C&En News, 2006 (September 25), 84 (39), p 90

  55. Visual artificial tongue for quantitative metal cation analysis by an off-the-shelf dye array, Lee, J.W.; Lee, J.S.; Kang, M.; Su, A. I.; Chang, Y. T. Chem. Eur. J. 2006, 12, 5691-5696. [link] 

  56. Solid-phase synthesis of styryl dyes and their application as amyloid sensors, Li, Q.; Lee, J. S.; Ha, C.; Park, C.B.; Yang G.; Gan, W. B.; Chang, Y. T. Angew. Chem., Int. Ed. Engl.2004, 43, 6331-6335. [link]